Interleukin-8-251T > a, interleukin-1α-889C > t and apolipoprotein e polymorphisms in Alzheimer's disease
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چکیده
منابع مشابه
Interleukin-8-251T > A, Interleukin-1α-889C > T and Apolipoprotein E polymorphisms in Alzheimer’s disease
An inflammatory process has been involved in numerous neurodegenerative disorders such as Parkinson's disease, stroke and Alzheimer's disease (AD). In AD, the inflammatory response is mainly located in the vicinity of amyloid plaques. Cytokines, such as interleukin-8 (IL-8) and interleukin-1α (IL-1α), have been clearly involved in this inflammatory process. Polymorphisms of several interleukin ...
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Introduction: IL-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (CRS) as well as nasal polyposis (NP). The ability of individuals in producing IL-8 is partially determined by IL-8-251 A/T polymorphism. Hence, the aim of the present study was to investigate the association between IL-8-251 A/T and CXCR2 +1208 C/T genes ...
متن کاملAssociation between Interleukin-8 -251T/A Polymorphism and Endometriosis in Iranian Women
Bachground: Endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. IL-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. The aim of this study was to investigate the association between -251T/A polymorphism in the IL-8 gene and endometriosis risk in Ira...
متن کاملinterleukin-8-251 a/t and cxcr2 +1208 c/t genes polymorphisms in chronic rhinosinusitis
introduction: il-8 is one of the pro-inflammatory cytokines which can play an essential role in the pathogenesis of chronic rhinosinusitis (crs) as well as nasal polyposis (np). the ability of individuals in producing il-8 is partially determined by il-8-251 a/t polymorphism. hence, the aim of the present study was to investigate the association between il-8-251 a/t and cxcr2 +1208 c/t genes p...
متن کاملevaluation of interleukin-8 −251 t/a polymorphisms in visceral leishmaniasis
background: interleukin (il)-8 plays important roles in the recruitment and activation of immune cells during visceral leishmaniasis (vl). genetic variations in il-8 modulate the expression of il-8 protein and may be associated with vl. this study aimed to evaluate polymorphisms at the il-8 −251 position in vl patients. methods: this cross-sectional study was performed on three groups: leishman...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2010
ISSN: 1678-4685,1415-4757
DOI: 10.1590/s1415-47572010005000098